Kinesin, 30 years later: Recent insights from structural studies
نویسندگان
چکیده
منابع مشابه
Rhodopsin: insights from recent structural studies.
The recent report of the crystal structure of rhodopsin provides insights concerning structure-activity relationships in visual pigments and related G protein-coupled receptors (GPCRs). The seven transmembrane helices of rhodopsin are interrupted or kinked at multiple sites. An extensive network of interhelical interactions stabilizes the ground state of the receptor. The ligand-binding pocket ...
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KNO scaling, i.e. the collapse of multiplicity distributions Pn onto a universal scaling curve manifests when Pn is expressed as the distribution of the standardized multiplicity (n− c)/λ with c and λ being location and scale parameters governed by leading particle effects and the growth of average multiplicity. At very high energies, strong violation of KNO scaling behavior is observed (pp̄) an...
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Phototransduction in vertebrate photoreceptor cells mediated by rhodopsin is one of the most comprehensively examined G protein-coupled receptor (GPCR) signaling pathways. The signal transduction pathway can be mapped from the initial absorption of light to conformational changes within rhodopsin, through activation of the G protein transducin, and to the ultimate closure of the cation cGMP-gat...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2015
ISSN: 0961-8368
DOI: 10.1002/pro.2697